Job Description

GENERAL SUMMARY/ OVERVIEW STATEMENT:

Cardiac arrest, atherosclerosis, myocardial infarction, and strokeaffect more than 40 million people in the United States and cardiovasculardisease is the number one cause of morbidity and mortality globally. Ourlaboratories are interested in understanding the underlying molecularmechanisms that contribute to the development of cardiovascular disease. Through these mechanistic studies we hope toidentify novel therapeutic targets to treat and prevent heart disease. We carry out experiments both in vitro and in vivo using multiple different cell-based assays and mouse modelsto understand the roles that specific proteins have in vascular disease andcardiac arrest. This position willrequire the handling of mice and carrying out relevant procedures on mice. Common techniques include RNA isolation, cDNAsynthesis, qPCR, Western blots and protein isolation, sterile tissue culture,genotyping, mouse dissection, and echocardiography. The research technician will be involved inall aspects of the research process from designing and executing experiments,to analyzing and presenting data, to writing the final research papers.

Thisposition is ideally targeted towards a candidate interested in pursuing acareer in academic medicine or biomedical research, but all that are interestedare encouraged to apply. We ask for a two-year commitment. Our laboratories have mentored numerousstudents as they transition to either medical school or graduate school. Dr. Ichinose is an anesthesiologist andphysician-scientist and a full professor at Harvard Medical School. Dr. Malhotra is a cardiologist andphysician-scientist and an Assistant Professor at Harvard Medical School.

PRINCIPAL DUTIES AND RESPONSIBILITIES:

Please note, the functions below are representative of major duties that are typically associated with these positions. Specific responsibilities may vary based upon departmental needs. Similarly, not all duties that have been outlined will be assigned to each position.

* The handling of mice and carrying out relevant procedures on mice
* Common laboratory techniques include RNA isolation, cDNA synthesis, qPCR, Western blots and protein isolation, sterile tissue culture, genotyping, mouse dissection, and echocardiography
* The research technician will be involved in all aspects of the research process from designing and executing experiments, to analyzing and presenting data, to writing final research papers
* Maintains laboratory notebook
* Participates in weekly lab meetings and present data
* Understands and applies basic scientific techniques
* Conducts analysis of results and may begin interpretation of results
* Sets up and prepares routine experiments as directed
* Prepares lab reagents, chemicals, instruments and equipment
* Assists with organizing materials for publication or presentation
* Maintains and orders supplies

SKILLS/ABILITIES/COMPETENCIES REQUIRED:

* Ability to work independently and as a team member
* Must be highly organized
* Must have excellent interpersonal, speaking and writing skills
* Understanding of laboratory practices and procedures preferred

EDUCATION:

* Bachelors degree required.

EXPERIENCE:

* New graduates with some lab experience (via course work, internships, etc.) or those without any prior research experience will be considered for the Research Technician I position outlined above.
* Prior molecular biology lab experience is strongly recommended, but not required
* Time Commitment: 2-year commitment is preferred.

SUPERVISORY RESPONSIBILITY (if applicable):

* none

Massachusetts General Hospital is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. Applications from protected veterans and individuals with disabilities are strongly encouraged.
EEO Statement
Massachusetts General Hospital is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. Applications from protected veterans and individuals with disabilities are strongly encouraged