Scientific Associate Director, Biocatalysis
Posted on: 5 Mar 2021
New Brunswick, NJ
Job Description
At Bristol Myers Squibb, we are inspired by a single vision transforming patients lives through science. In oncology, hematology, immunology and cardiovascular disease and one of the most diverse and promising pipelines in the industry each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.
As a Scientific Associate Director, Biocatalysis, in the Chemical Process Development Technologies Group, you will be responsible to build, drive, and lead biocatalysis efforts in the design and implementation of safe, efficient, and robust chemical processes for the synthesis of drug candidates. Candidates will have a strong innovation focused mindset with experience in applying and developing novel applications of biocatalysts in a team based environment of chemists, chemical engineers, and analytical chemists.
Critical to these activities will be the requirement to manage external partners for biocatalyst evolution and development as well as guide internal development resources, gathering fundamental process knowledge about enzyme catalyzed reactions, address scale up challenges, and transitioning such processes to manufacturing.
Qualifications/Requirements:
The qualified candidates will have a Ph.D. in organic chemistry with 7 to 10 years of additional related research/process experience in biocatalysis.
Candidates must possess a strong background in the theory and practice of synthetic organic chemistry, possess excellent problem solving skills, and demonstrate a thorough understanding of synthetic methods and reaction mechanisms. Of equal importance is deep expertise in the application of biocatalytic transforms for chemical process development, the principles that govern them, as well as knowledge about the external landscape and emerging biocatalytic technologies is desired. Good oral and written communication skills and an ability to work in a collaborative team environment with a diverse group of stakeholders across disciplines, both internal and external, is required. Also, a record of achievements in biocatalytic process development and a demonstrated ability to perform assigned tasks through rigorous data collection and applying analytical tests and instrumentation in the laboratory. Must have expertise in the purification and characterization of organic compounds (i.e. HPLC, NMR, MS, and IR).
Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.
Bristol-Myers Squibb
New York, New York
Bristol-Myers Squibb Company discovers, develops, licenses, manufactures, markets, distributes, and sells biopharmaceutical products worldwide. The company offers drugs in oncology, immunoscience, cardiovascular, and fibrotic diseases. The company’s products include Opdivo, a biological product for anti-cancer indications; Eliquis, an oral inhibitor targeted at stroke prevention in adult patients with non-valvular atrial fibrillation, and the prevention and treatment of venous thromboembolic disorders; and Orencia, a biological product for adult patients with moderately to severely active RA and prostate-specific antigen, as well as reducing signs and symptoms in certain pediatric patients with moderately to severely active polyarticular juvenile idiopathic arthritis.
It also provides Sprycel, a tyrosine kinase inhibitor for the treatment of Philadelphia chromosome-positive chronic myeloid leukemia; Yervoy, a monoclonal antibody for the treatment of patients with unresectable or metastatic melanoma; Empliciti, a humanized monoclonal antibody for the treatment of multiple myeloma; and Baraclude, an oral antiviral agent for the treatment of chronic hepatitis B. In addition, the company offers Reyataz, a protease inhibitor for the treatment of human immunodeficiency virus (HIV) and Evotaz; Sustiva franchise, a non-nucleoside reverse transcriptase inhibitor for the treatment of HIV; and Daklinza NS5A replication complex inhibitor, Sunvepra NS3 protease inhibitor, and Beclabuvir NS5B inhibitor. It sells products to wholesalers, retail pharmacies, hospitals, government entities, and medical profession. It has collaboration agreements with Nektar Therapeutics; Janssen Pharmaceuticals, Inc.; Biocartis Group NV.; and FameWave Ltd.
The company was formerly known as Bristol-Myers Company and changed its name to Bristol-Myers Squibb Company in 1989. Bristol-Myers Squibb Company was founded in 1887 and is headquartered in New York, New York.
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IndustryBiopharmaceuticals
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No. of Employees23, 300
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Website
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Jobs Posted1641
