Job Description

Janssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies is recruiting for a Scientist, Antibody Engineering, located in Spring House, PA. 

At the Janssen Pharmaceutical Companies of Johnson & Johnson, we are working to create a world without disease. Transforming lives by finding new and better ways to prevent, intercept, treat and cure disease inspires us. We bring together the best minds and pursue the most promising science.  We are Janssen. We collaborate with the world for the health of everyone in it. Learn more at www.janssen.com and follow us @JanssenGlobal. Janssen Research & Development, LLC is part of the Janssen Pharmaceutical Companies.

The Biologics Discovery group within the Therapeutics Discovery (TD) organization of Janssen R&D is engaged in the discovery and optimization of novel antibody and antibody based molecular entities in partnership with the all therapeutic areas of Janssen. In this role you will learn about the exciting science Janssen is exploring in lead engineering that will feed into antibody and other therapeutic modalities. 

This position offers a phenomenal opportunity for you to engage in the discovery of next generation Biotherapeutics to address unmet medical needs as part of an outstanding team of scientists! Janssen provides competitive benefits and an unrivaled network of colleagues and company-sponsored activities while supporting employees in maintaining a healthy work-life balance. 

Key Responsibilities:

Design and clone antibody and protein based molecular entities
Support the broad lead engineering efforts in the modality agnostic Therapeutics Discovery organization
Perform and expand established assays as well as develop and optimize new assays. Responsibilities will include cloning, plasmid scale-up, plasmid QC, cell culture, reagent preparation, E. coli and mammalian cell culture, ELISA and other binding assays and flow cytometry.
Be able to independently process data, interpret results, update the database, and present results to applicable functional groups.
Manage laboratory operations including such as reviewing of experimental protocols and equipment manuals, writing protocols, ordering of reagents and supplies, inventory management, instrument QC, scheduling of equipment maintenance, safety inspections
Train new hires and mentor other scientists, contractors, and co-op students

Qualifications

MSc or PhD or equivalent in Molecular Biology, Biochemistry, Biotechnology, Biomedical Engineering, structural biology or related field is required
At least 4 years of relevant laboratory experience is preferred
In-depth understanding and experience of antibody engineering, managing incoming requests, conducting design and registering plasmids in a central database system is preferred
Experience in molecular biology techniques including bi-, multi-specifics, scFv, and/or chimeric antigen receptor (CAR) construct design and cloning is preferred
Demonstrated experience working in a cross-functional organization
Maintain accurate inventory of generated plasmids, lab notebooks, and other records and writing of technical reports, summaries, protocols, and manuscripts are preferred
Strong written and oral communication skills are required
Experience with protein production using transient transfection/stable cell line generation using CHO and HEK-293 is preferred
Proficient knowledge of cellular/molecular biology, common biology laboratory assays such as ELISA, Luminex, and biolayer interferometry (Octet) and other assays are preferred

At Johnson & Johnson, we’re on a mission to change the trajectory of health for humanity. That starts by creating the world’s healthiest workforce. Through cutting-edge programs and policies, we empower the physical, mental, emotional, and financial health of our employees and the ones they love. As such, candidates offered employment must show proof of COVID-19 vaccination or secure an approved accommodation prior to the commencement of employment to support the well-being of our employees, their families and the communities in which we live and work.

For more information on how we support the whole health of our employees throughout their wellness, career and life journey, please visit www.careers.jnj.com.

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.