Job Description

Position Summary:

Mesa Biotech, part of Thermo Fisher is a fast growing, ISO certified, FDA-cleared, medical device company that has achieved a dramatic simplification in the complexity of DNA and RNA molecular testing. Our patented technology provides everything needed to conduct rapid molecular tests at the point-of-care. The palm-sized, reusable dock and disposable test cassette form a user-friendly system for use anywhere, from the physician2019s office to the patient2019s home.

We are seeking a Staff Scientist, Chemistry to actively participate and support the development of point of care molecular diagnostic kits in a demanding, fast-paced environment. You will work independently and closely with other scientists to design and develop multiplexed PCR amplification for point of care settings. The Staff Scientist, Chemistry will work to develop rapid, point-of-care molecular diagnostic assay products. Daily activities include: the initial viral and bacterial culture assay development to meet product requirements, feasibility experimentation, composition of SOP documents and product transfer into manufacturing, verification and validation testing, and on-going support of transferred products.

Key Responsibilities:

* Experience developing and optimizing viral and bacterial culture assay to ensure proper quality and other performance requirements are achievable
* Experience recombinant viral assay to ensure proper quality and other performance requirements are achievable
* Experience with PCR assay and Real time PCR quantification method
* Ability to work with BSLII pathogen culture and understanding of molecular biology laboratory and microbiology workflows and RNase-free handling
* Experience developing and optimizing lateral flow strip chemistry that is required for detection of post-amplification materials and result interpretation
* Ability to work and communicate in an inter-department effort with engineering personnel to implement and test new design features and give the biological perspective on proposed engineering designs and impact to chemistry
* Ability to write and maintain standard operating procedures (SOPs), manufacturing instructions, quality control test methods, and experience with document control procedures
* Conduct product scale-up and transfer into manufacturing, with any required support troubleshooting
* Conduct verification and validation testing using clinical samples and contrived viral samples
* Ability to lead projects and supervise a small team of other scientists, associate scientists, technicians, etc.

Minimum Requirements/Qualifications:
* At least two years of post-doctoral research laboratory experience, or B.S. degree in Molecular Biology, Biology or Biochemistry with a minimum of 5 years relevant industry experience
* Proven experience developing RT-PCR based assays from concept through technical transfer and commercial launch Personal attributes:
* Have excellent presentation skills
* Strong writing skills, able to maintain laboratory notebook
* Be able to work with internal and external team members
* Excellent laboratory skills
* Able to solve problems of a complex nature
* Effectively communicate results and development updates to management through meetings and reports

Non-Negotiable Hiring Criteria:

* At least two years of post-doctoral research laboratory experience, or B.S. degree in Molecular Biology, Biology or Biochemistry with a minimum of 5 years relevant industry experience
* Proven experience developing RT-PCR based assays from concept through technical transfer and commercial launch
* Deep understanding of technical concepts of RT-PCR assay development
* Mentor and 201Clead by example201D for R&D and assay development project team members
* Ability to work independently
* Work within an integrated multidisciplinary laboratory and be able to work with other scientists, technicians, engineers, and students on the tea
* Interact and work effectively with a demanding, fast-paced biotech startup environment
* Ability to work long hours and execute under pressure with short turnaround times
* Ability to speak, write, and use all office equipment including scanner and printer, phone, computer, etc.
* Available nights, weekends, and holidays when needed
* Ability to lift up to 30lbs