AbbVie

Associate Scientist II/ Scientist I, Chemical Biology and Proteomics

Posted on: 28 Mar 2021

Chicago, IL

Job Description

About AbbVie
AbbVies mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on peoples lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, womens health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn.

We are seeking a highly-motivated multidisciplinary scientist, preferably with pharma/biotech experience, to join the Protein Degradation Platform Team in North Chicago, IL. The successful candidate will be adept in applying chemical biology techniques combined with analytical tools for addressing drug discovery program needs within the Proteasome Sciences team. The successful candidate will also enhance assay readouts to support AbbVie's drug discovery pipeline while interacting with a broad range of therapeutic area scientists to deliver key data that accelerates the delivery of novel medicines to patients in need.

Key Responsibilities:

* Plan and execute experiments to interrogate mechanisms of targeted protein degradation.
* Prepare samples from cells and tissues for multiple downstream analyses such as mass spectrometry.
* Calibration and routine maintenance of LC-MS systems for proteomics
* Maintain a high level of productivity in the laboratory setting.
* Demonstrate a high degree of responsibility in maintaining scientific standards and safe laboratory practices.
* Keep accurate and current records of research and/or project related activities according to AbbVie policies.
* Interface and collaborate with colleagues and project teams in therapeutic areas to determine appropriate chemical biology approach to best address the needs

Qualifications
Position will be hired based on level of experience and education.

* BS or MS in Analytical Chemistry, Chemical Biology, or closely related field with typically 0+ years (MS); or 2+ years (BS) of job-related experience
* Hands-on experience with HPLC and mass spectrometry
* Familiarity with analytical chemistry sample preparations (e.g., serial dilutions, buffer preparations, tryptic digestions)
* Effective verbal and written communication skills and ability to interact with scientists outside of field.
* Motivated, independent, and productive problem solver
* High attention to detail, creativity in problem-solving, strong interpersonal skills, and ability to successfully work independently at the lab bench
* Experience in proteomics (sample preparation, data acquisition, data analysis)
* 1-3 years industry experience is preferred

Significant Work Activities
N/A
Travel
No
Job Type
Experienced
Schedule
Full-time
Job Level Code
IC
Equal Employment Opportunity
At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.

AbbVie

Chicago, IL

AbbVie Inc. discovers, develops, manufactures, and sells pharmaceutical products in the United States, Japan, Germany, Canada, Italy, Spain, the Netherlands, the United Kingdom, Brazil, and internationally. The company offers HUMIRA, a therapy administered as an injection for autoimmune and intestinal Behçet's diseases; IMBRUVICA to treat adult patients with chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), mantle cell lymphoma, waldenström’s macroglobulinemia, marginal zone lymphoma, and chronic graft versus host disease; VENCLEXTA, a BCL-2 inhibitor used to treat adults with CLL or SLL; VIEKIRA PAK, an interferon-free therapy to treat adults with genotype 1 chronic hepatitis C virus (HCV); TECHNIVIE to treat adults with genotype 4 HCV infection; and MAVYRET to treat patients with chronic HCV genotype 1-6 infection.

It also provides KALETRA, an anti-human immunodeficiency virus (HIV)-1 medicine used with other anti-HIV-1 medications to maintain viral suppression in HIV-1 patients; NORVIR, a protease inhibitor indicated in combination with other antiretroviral agents to treat HIV-1; and SYNAGIS to prevent respiratory syncytial virus infection at-risk infants. In addition, the company offers AndroGel, a testosterone replacement therapy for males; CREON, a pancreatic enzyme therapy for exocrine pancreatic insufficiency; Synthroid to treat hypothyroidism; and Lupron to treat prostate cancer, endometriosis, and central precocious puberty, as well as anemia.

Further, it provides Duopa and Duodopa, a levodopa-carbidopa intestinal gel to treat Parkinson’s disease; Sevoflurane, an anesthesia product; and ORILISSA, a non-peptide small molecule gonadotropin-releasing hormone antagonist for women with moderate to severe endometriosis pain. It has collaborations with Alector, Inc.; Janssen Biotech, Inc.; Galapagos; Bristol-Myers Squibb Company; and Calico Life Sciences LLC. The company was incorporated in 2012 and is headquartered in North Chicago, Illinois.

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