A Senior Associate Scientist (R2) position is available in the Upstream Process Development group of Bioprocess R&D in Chesterfield, MO. Were seeking a passionate and creative individual to join a dynamic team of scientists and engineers focused on developing robust, scalable, and high productivity cell culture processes for the manufacture of biological therapeutics for early- and late-phase clinical programs. The work will also involve working with pilot scale, commercial and clinical production facilities to ensure accurate technology transfer and successful large-scale production. You may also be involved in cutting edge technology development projects that seek to discover broadly applicable methods to intensify microbial/ mammalian cell culture or cell free systems.
ROLE RESPONSIBILITIES
* Design, plan and execute fermentation/ cell culture experiments in shake flasks, bench-top bioreactors, and other appropriate scale-down equipment in the development laboratory.
* Ensures timely, effective, and high-quality documentation in electronic laboratory notebooks and internal technical reports.
* Communicate results and findings to stake-holders on a regular basis; presents data/strategy to colleagues and management in internal and external venues (technical meetings, project team meetings, and conferences, etc.) as appropriate.
* Assist in or lead the technology transfer of manufacturing processes to pilot, clinical, and commercial facilities.
* Provide support and troubleshoot during manufacturing campaigns as needed.
* Work collaboratively with colleagues both within the group and cross-functionally; contribute to maintaining and improving upon our safe, effective and efficient lab operations.
BASIC QUALIFICATIONS
* BS/BA with 2-4 years of experience, or MS with 0-2 years of experience in Biotechnology, Microbiology, Cell Biology, Chemical/Biochemical Engineering, or other related disciplines.
* Relevant research experience in a laboratory setting is required.
* Ability to grasp scientific concepts, interpret complex data, and formulate new hypothesis.
* Requires competency in aseptic laboratory technique and the ability to design and carry out complex experiments and interpret data.
* Requires demonstrated effectiveness in collaborative projects, and ability to communicate effectively with scientists and management in a highly matrixed organization.
PREFERRED QUALIFICATIONS
* Practical knowledge and/or experience with microbial/mammalian cell culture metabolism, scale up, GLP/GMP practices, and technology transfers to pilot/commercial sites.
* Team oriented, with excellent oral and written communication skills.
* Well organized and great attention to detail.
Other Job Details:
* Last Date to Apply for Job: April 5, 2021
* Eligible for Employee Referral Bonus: YES
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Research and Development
LI-PFE
New York, New York
Pfizer Inc. develops, manufactures, and sells healthcare products worldwide. It offers medicines and vaccines in various therapeutic areas, including internal medicine, vaccines, oncology, inflammation and immunology, and rare diseases under the Lyrica, Chantix/Champix, Eliquis, Ibrance, Sutent, Xalkori, Inlyta, Xtandi, Enbrel, Xeljanz, Eucrisa, BeneFix, Genotropin, and Refacto AF/Xyntha brands. The company also provides consumer healthcare products that comprise over-the-counter medicines, including dietary supplement products under the Centrum, Caltrate, and Emergen-C names; pain management products under the Advil and ThermaCare names; gastrointestinal products under the Nexium 24HR/Nexium Control and Preparation H names; and respiratory and personal care products under the Robitussin, Advil Cold & Sinus, and ChapStick names. In addition, it offers products that would lose or have lost marketing patent protection; branded generic products; generic sterile injectable products; biosimilars; and anti-infectives under the Lipitor, Premarin family, Norvasc, Lyrica, Celebrex, Viagra, Inflectra/Remsima, Zyvox, Vfend, Revatio, Inspra, Medrol, Sulperazon, Fragmin, Tygacil, Nivestim, and Retacrit, Ixifi Infliximab BS names.
Further, the company is also involved in the contract manufacturing business. It serves wholesalers, retailers, hospitals, clinics, government agencies, pharmacies, and individual provider offices, as well as disease control and prevention centers. The company has collaboration and/or co-promotion agreements with Bristol-Myers Squibb Company, Astellas Pharma US, Inc., and Oncolytics Biotech Inc.; licensing agreement with BionTech AG; strategic alliance with Verily Life Sciences LLC; and collaboration agreements with Pfizer, Merck & Co., Inc., and Eli Lilly & Company, as well as with Merck KGaA and Nektar Therapeutics to develop a therapy for treating pancreatic cancer. Pfizer Inc. was founded in 1849 and is headquartered in New York, New York.