Job Description

At Bristol Myers Squibb, we are inspired by a single vision transforming patients lives through science. In oncology, hematology, immunology and cardiovascular disease and one of the most diverse and promising pipelines in the industry each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

Scientist - Upstream Scale-up Group

BIOLOGICS DEVELOPMENT

At Bristol Myers Squibb, we are inspired by a single vision transforming patients lives through science. In oncology, hematology, immunology and cardiovascular disease and one of the most diverse and promising pipelines in the industry each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

The Scientist position will be part of the Upstream Scale-up Group in Devens, MA to scale-up and execute upstream processes for late-stage biologics in BMSs robust pipeline. This role will work closely with the downstream team, analytical team, as well as with manufacturing sites within the BMS network to deliver robust, scalable, and economical processes for late-stage clinical and commercial supply. This position will report to the Associate Director of Pilot Plant Network and will be based in Devens, MA.

Key Responsibilities

* Use scientific expertise to provide solutions to a broad range of difficult problems.
* Introduce, evaluate, and implement innovative new process technologies to support platform evolution.
* Take a part in daily operations in the Upstream Scale-up Lab, including bioreactor fill/harvest, inoculation, daily sampling, feeding, and monitoring/troubleshooting
* Prepare/review technical documents including campaign summary reports, batch records, and SOPs.
* Maintain a safe work environment in the Scale-up lab
* Participate in cross-functional teams to support process investigations, process development, scale-up, and tech transfer to clinical and commercial manufacturing
* Collaborate with partner Downstream Scale-up Lab and Upstream PD to ensure smooth process and material transfer
* Track performance of Scale-up data against development scale to aid PD teams in the development of scale-down models

Qualifications

* B.S., M.S., or Ph.D. in Chemical/Biochemical Engineering, Biotechnology, Biochemistry, or related biologics fields
* Minimum 5 years of experience in Process Development or related field
* Strong knowledge of upstream process development and unit operations, including mammalian cell culture and bioreactors is required.
* Working knowledge of cGMP and prior experience in single-use manufacturing and automation are preferred.
* Knowledge of downstream processing
* Knowledge of analytical techniques such as HPLC, CE, or others related to glycoprotein attributes
* Knowledge of statistics, design of experiment, and data analysis
* Excellent oral and written communication skills
* Capability for travel up to 10-20%

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application, or any part of the recruitment process direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.