Job Description

Job Title: Scientist II, Protein Production

Requisition ID: 148001BR

When you join us at Thermo Fisher Scientific, you2019ll be part of a smart, driven team that shares your passion for exploration and discovery. With revenues of more than $20 billion and the largest investment in R&D in the industry, we give our people the resources and opportunities to make significant contributions to the world.

How will you make an impact?

You will work in a team-based environment to produce and qualify purified proteins for global use in research and commercial products in the life sciences industry.

What will you do?

The successful candidate demonstrates a sense of urgency, contagious optimism and a 201Ccan do201D attitude. They lead by example and hold themselves and others accountable, while maintaining productive and professional relationships within the team. The primary responsibilities are as follows:

* Responsible for manufacturing product(s) in a lab setting following standard operating procedures. Will utilize basic laboratory techniques, calculations, materials measurement, operation of laboratory equipment and record keeping necessary to manufacture products.
* Will perform column purification/ chromatography, buffer preparation, SDS-Page Analysis, Western Blotting, and other protein characterization techniques.
* Responsible for Batch Data Records, notebooks, customer reports (as required) and work order documents.
* Utilize specialized technical knowledge and skills to make detailed observations and analyze data to ensure within operating parameters. Advise manager of factors that may affect quality of product. Suggest and execute on options/ideas for corrective actions.
* Maintain equipment, product inventories and related records as assigned. Note variances on manufacturing documents; audit and evaluate process documents and propose revisions. Complete, distribute and file records as required in accordance with Document Control Practices.
* Identify potential issues in the production process, report findings to team management and lead troubleshooting and resolution process.
* Recognize deviations to the process and/or desired specifications and manage problem reports as necessary. Ability to collaborate with other technical subject matter experts to determine root cause and make recommendations to changes in the process to mitigate reoccurrence.
* Write technical documents which include standard operating procedures and manufacturing batch records.
* Lead process improvement projects, or product transfer projects to resolve a technical issue, reduce process scrap or improve productivity.
* Collaborate effectively with support functions to achieve annual goals set

How will you get here?

Education

* Must have a Bachelor2019s degree in Biology, Chemistry, Biochemistry, or other related discipline with 3+ years of relevant protein purification experience.
* Master2019s degree in Biology, Chemistry, Biochemistry, or other related discipline with 1+ years of relevant protein purification experience preferred.

Experience

* Demonstrated proficiency in the use of scientific laboratory techniques, equipment and materials required. Experience in the use of standard laboratory techniques, including buffer preparation, column purification/ chromatography, SDS-Page Analysis, Western Blotting, and other protein characterization techniques.
* Expert level operation of GE AKTA FPLC protein chromatography equipment and/or NGC FPLC, and ability to write chromatography programs in Unicorn software or equivalent system.
* Ability to pack columns at large scale and preferred experience using TFF skid
* Experience with different modes of chromatography such as: affinity, ion-exchange, size exclusion, hydrophobic interaction. Understanding of protein/resin interactions and protein chemistry.

Knowledge, Skills, Abilities

* Strong collaborative skills and the ability to influence others without authority
* Is energized working in a fast-paced environment
* Consistent, dependable, and accurate in carrying out responsibilities
* Displays positive attitude toward job and others
* Results oriented and data driven
* Can identify anomalous results and escalate accordingly
* Demonstrated ability to carry out scientific procedures and make recommendations for improvement required.
* Greets challenge and change as opportunity
* Is curious, inquisitive, innovative, never satisfied with the status quo
* Proactive approach that anticipates needs and problems while creating solutions
* Excellent documentation and communication skills
* Regularly required to lift up to 20 pounds. May be required to lift weight of 45 pounds or more, with assistance and/or with equipment on occasion.
* May be required to stand for long periods of time while performing duties.
* Must be flexible to work varying schedules and hours as needed.
* Must be able to work safely with chemicals and hazardous materials.
* Must be able to work in +4C Cold-Room as required.

At Thermo Fisher Scientific, each one of our 75,000 extraordinary minds have a unique story to tell. Join us and contribute to our singular mission2014enabling our customers to make the world healthier, cleaner and safer.

Apply today! http://jobs.thermofisher.com

Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.