Scientist I, Analytical Bioassay Development, Gene Therapy
Posted on: 18 Jan 2021
Cambridge, MA
Job Description
Job Description
Bioassay group in Analytical Development at Biogen has an exciting opportunity for an innovative and self-motivated scientist to work on development of analytical methods for characterization of the AAV gene therapy products.
* The individual will focus on development and qualification of cell-based assays for measuring expression, potency, and other critical quality attributes of the targets of interest.
* Additional responsibilities include assessment and implementation of new analytical technologies, providing technical support to cross-function groups and external collaborators.
* The successful candidate will independently design, perform, and analyze experiments for multiple projects, and will work with other team members and external collaborators to support process development, product characterization, and manufacturing activities.
Qualifications
* Advanced mammalian cell culture skills.
* Strong cell and molecular biology background.
* Working knowledge of gene expression, qPCR, and immunochemistry methods.
* Experience with viral vectors, experience with AAV preferred.
* Excellent written and oral communication skills.
* Familiarity with various detection technologies, such as fluorescence, luminescence, ECL etc., is a plus.
* Ability to work independently with a sense of urgency while appropriately prioritizing multiple projects.
Education:
Bachelors Degree in biology or related field with 6-8 years of related experience
Masters degree in biology or related field with 4-6 years of related experience
Ph.D. in Biology or related field with 0-2 years of related experience
Additional Information
Bioassay group in Analytical Development at Biogen has an exciting opportunity for an innovative and self-motivated scientist to work on development of analytical methods for characterization of the AAV gene therapy products.
Biogen
Cambridge, MA
Biogen Inc. discovers, develops, manufactures, and delivers therapies for treating neurological and neurodegenerative diseases worldwide. The company offers TECFIDERA, AVONEX, PLEGRIDY, TYSABRI, and FAMPYRA for the treatment of multiple sclerosis (MS); SPINRAZA for the treatment of spinal muscular atrophy; and FUMADERM for the treatment of plaque psoriasis. It also provides BENEPALI, an etanercept biosimilar referencing ENBREL; FLIXABI, an infliximab biosimilar referencing REMICADE; and IMRALDI, an adalimumab biosimilar referencing HUMIRA. In addition, the company offers RITUXAN for the treatment of non-Hodgkin's lymphoma, chronic lymphocytic leukemia (CLL), rheumatoid arthritis, two forms of ANCA-associated vasculitis, and pemphigus vulgaris; RITUXAN HYCELA for non-Hodgkin's lymphoma and CLL; GAZYVA to treat CLL and follicular lymphoma; and OCREVUS for the treatment of primary progressive MS and relapsing MS, and other anti-CD20 therapies.
Further, it is involved in developing BIIB098, Opicinumab, and BIIB061 for MS and neuroimmunology; Aducanumab, Elenbecestat, BAN2401, BIIB092, BIIB076, and BIIB080 to treat Alzheimer's disease and dementia; BIIB092 and BIIB054 for treating Parkinson's disease and movement disorders; BIIB067, BIIB078, and BIIB110 to treat neuromuscular disorders; BIIB093, TMS-007, and Natalizumab to treat acute neurology; BIIB104 for treating neurocognitive disorders; BIIB074 and BIIB095 for pain; and Dapirolzumab pegol, BG00011, and BIIB059 for treating other diseases, which are under various stages of development.
The company offers products through its sales force and marketing groups. Biogen Inc. has collaboration agreements with Genentech, Inc., Eisai Co., Ltd., Alkermes Pharma Ireland Limited, Bristol-Myers Squibb Company, Acorda Therapeutics, Inc., AbbVie Inc., C4 Therapeutics, University of Pennsylvania, Applied Genetic Technologies Corporation, and others. The company was founded in 1978 and is headquartered in Cambridge, Massachusetts.
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IndustryBiotechnology
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No. of Employees7,800
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Website
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Jobs Posted445
