Scientist (non-PhD), Tumor Immunogenicity
Posted on: 26 Apr 2021
La Jolla, CA
Job Description
ROLE SUMMARY
Pfizer Cancer Immunology Discovery (CID) is within the Oncology division of Pfizer Worldwide Research & Development in La Jolla, CA. CID is dedicated to developing new protein therapeutics to improve human life by redirecting the immune system against cancer. CID researchers apply the latest scientific knowledge and novel approaches to discover truly innovative Immuno-Oncology therapeutics. We are seeking to hire a non-PhD Scientist for the Tumor Immunogenicity CID group.
ROLE RESPONSIBILITIES
Execution of cell-based functional and biochemical assays to select candidate molecules for clinical development or support combination strategies
Planning, establishing and executing functional and biochemical assays using a broad range of technologies such as multi-color flow cytometry, Incucyte cell imaging, primary cell cultures
Analyze, organize, and present results in small and large group meetings
Read relevant scientific literature to aid in experimental design
BASIC QUALIFICATIONS
B.S. degree with 6+ years’ experience or M.S. degree with 5+ years' experience (M.S. preferred)
Experience in the fields of immunology, cell biology and/or genetics
Ability to plan and execute and in vitro and/or in vivo/ex vivo experiments with minimal supervision
Expertise in standard immunologic techniques
Experience with flow cytometry, qRT-PCR, MSD, Nano string and cytotoxic assays
Technical expertise with immune cell-based functional assays (e.g. activation, differentiation, proliferation, and suppression assays by using monocyte/ macrophages, T-cells, or dendritic cells)
Immune phenotyping tumor associated immune cells from primary human tumor samples by flow cytometry
Excellent organization and planning skills, the ability to work in a fast-paced environment independently or as part of a team, good verbal and written communication, and strong motivation with a dedicated work ethic
PREFERRED QUALIFICATIONS
Experience in CRISPR technology and lentiviral transduction
Experience with various murine tumor and/or infectious disease models
Experience with human PBMC and mammalian cell culture
PHYSICAL/MENTAL REQUIREMENTS
Standing, sitting, bending, lifting, walking in a laboratory or vivarium setting.
Use of Personal Protective Equipment (PPE) in a BSL-2 laboratory; additional PPE requirements when working in vivarium barrier suites.
Standard business office conditions; sitting, standing as appropriate
OTHER JOB DETAILS
Eligible for Employee Referral Bonus
Pfizer
New York, New York
Pfizer Inc. develops, manufactures, and sells healthcare products worldwide. It offers medicines and vaccines in various therapeutic areas, including internal medicine, vaccines, oncology, inflammation and immunology, and rare diseases under the Lyrica, Chantix/Champix, Eliquis, Ibrance, Sutent, Xalkori, Inlyta, Xtandi, Enbrel, Xeljanz, Eucrisa, BeneFix, Genotropin, and Refacto AF/Xyntha brands. The company also provides consumer healthcare products that comprise over-the-counter medicines, including dietary supplement products under the Centrum, Caltrate, and Emergen-C names; pain management products under the Advil and ThermaCare names; gastrointestinal products under the Nexium 24HR/Nexium Control and Preparation H names; and respiratory and personal care products under the Robitussin, Advil Cold & Sinus, and ChapStick names. In addition, it offers products that would lose or have lost marketing patent protection; branded generic products; generic sterile injectable products; biosimilars; and anti-infectives under the Lipitor, Premarin family, Norvasc, Lyrica, Celebrex, Viagra, Inflectra/Remsima, Zyvox, Vfend, Revatio, Inspra, Medrol, Sulperazon, Fragmin, Tygacil, Nivestim, and Retacrit, Ixifi Infliximab BS names.
Further, the company is also involved in the contract manufacturing business. It serves wholesalers, retailers, hospitals, clinics, government agencies, pharmacies, and individual provider offices, as well as disease control and prevention centers. The company has collaboration and/or co-promotion agreements with Bristol-Myers Squibb Company, Astellas Pharma US, Inc., and Oncolytics Biotech Inc.; licensing agreement with BionTech AG; strategic alliance with Verily Life Sciences LLC; and collaboration agreements with Pfizer, Merck & Co., Inc., and Eli Lilly & Company, as well as with Merck KGaA and Nektar Therapeutics to develop a therapy for treating pancreatic cancer. Pfizer Inc. was founded in 1849 and is headquartered in New York, New York.
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IndustryBiopharmaceuticals
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No. of Employees92,400
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Website
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Jobs Posted2412
