Job Description

Job Title: Manufacturing Specialist III, Protein Purification

Requisition ID: 154093BR

When you2019re a part of the team at Thermo Fisher Scientific, you2019ll do important work, like helping customers in finding cures for cancer, protecting the environment or making sure our food is safe. Your work will have real-world impact, and you2019ll be supported in achieving your career goals.

How will you make an impact?

You will be part of a team performing all tasks related to protein purification. You will work in a clean, controlled manufacturing facility under GMP conditions using protein purification equipment and analytical techniques.

What will you do?

The successful candidate demonstrates a sense of urgency, contagious optimism and a 201Ccan do201D attitude. They lead by example and hold themselves and others accountable, while maintaining productive and professional relationships within the team. The primary responsibilities are as follows:

* Manufacture in a lab setting following standard operating procedures. Will utilize basic laboratory techniques, calculations, materials measurement, operation of laboratory equipment and record keeping necessary to manufacture products in a GMP environment.
* Perform column purification/chromatography, tangential flow filtration (TFF), buffer preparation, SDS-Page Analysis, Western Blotting, and other protein characterization techniques.
* Responsible for Batch Data Records, notebooks (if required) and work order documents.
* Utilize specialized technical knowledge and skills to make detailed observations and analyze data to ensure within operating parameters. Advise manager of factors that may affect quality of product.
* Maintain equipment, product inventories and related records as assigned.
* Complete, distribute and file records as required in accordance with Document Control Practices under GMP conditions.
* Safety:
* Comply with all company safety regulations and procedures and report non-compliance.
* Serve as an effective safety steward by ensuring accurate reporting of near misses and attending safety trainings.
* Maintain knowledge of SDSs for relevant products/materials.
* Operate a safe work environment through continuous safety awareness and full compliance to all EH&S programs and activities.
* Identify potential issues in a process; report findings to team management, perform troubleshooting (as required) and identify solutions.
* Modify technical documents which include standard operating procedures and manufacturing batch records within the requirements of the quality management system.
* Perform process improvement projects (as required) to reduce process scrap or improve quality and productivity.
* May perform other related duties as required and/or assigned.

How will you get there?

Education

* Must have Bachelor2019s degree in Biology, Chemistry, Biochemistry, or other related discipline.

Experience

* 5+ years2019 experience in a manufacturing environment or R&D laboratory.
* Experienced operator of AKTA FPLC protein chromatography equipment and Unicorn software or equivalent system.
* Experience with different modes of chromatography such as: affinity, ion-exchange, size exclusion, hydrophobic interaction. In depth understanding of protein/resin interactions.
* Experience with execution of validation protocols is preferred.
* Experience with ISO 9001 and Pharmaceutical GMP strongly preferred.

Knowledge, Skills, Abilities

* Consistent, dependable and accurate in carrying out responsibilities
* Displays positive attitude toward job and others
* Follows and provides direction accurately and efficiently
* Excellent documentation and communication skills
* Results oriented and data driven
* Demonstrated ability to carry out scientific procedures and make documented improvements
* Demonstrated problem-solving skills
* Theoretical understanding of protein chemistry, methods and techniques
* Proactive approach that anticipates needs and problems while creating solutions
* Strong collaborative skills and the ability to influence others without authority
* Working knowledge of manufacturing related computer software preferred
* Intermediate Excel skills

Working Conditions

* Works in a clean, controlled, manufacturing lab environment with specialized equipment.
* Regularly required to lift up to 20 pounds. May be required to lift weight of 45 pounds or more, with assistance and/or with equipment on occasion.
* May be required to stand for long periods of time while performing duties.
* Must be flexible to work varying schedules and hours as needed.
* Must be able to work safely with chemicals and hazardous materials.
* Must be able to work in +400BAC Cold-Room.

At Thermo Fisher Scientific, each one of our 75,000 extraordinary minds have a unique story to tell. Join us and contribute to our singular mission2014enabling our customers to make the world healthier, cleaner and safer.

Apply today! http://jobs.thermofisher.com

Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.