Job Description

Job Description

The Biologics Upstream Process Development group within Biologics Process Research & Development handles the development of upstream processes and chemically defined media for both early and late stage biologics, as well as implementing these processes for clinical manufacture. We work closely with colleagues in Discovery, Pre-clinical, and Early Development to rapidly develop manufacturing processes for diverse biotherapeutics, and efficiently manufacture material to supply clinical trials. We also manage late stage/commercial process development and development of new manufacturing technologies. We work with our partners at our Company's Manufacturing Division to commercialize and launch new products.

As a Scientist, you will work with a highly collaborative team of scientists and engineers to design and develop upstream cell culture processes and implement manufacturing processes for our early and late stage clinical and commercial pipeline. This position will also have the opportunity to apply and integrate innovation into our cell culture medium development, particularly, advancing platform media for fed batch and perfusion processes, developing media concentrates and new media formats for implementation in manufacturing, and supporting deeper understanding of the relationship between media and cell metabolism.

Primary Duties:

* Support pipeline programs for first-in-human and commercial processes, efficiently developing high yield, robust, and scalable cell culture processes.

* Scale-up and technology transfer of bioprocesses to manufacturing facilities.

* Advance fed batch and perfusion media formulations by leveraging spent media analysis and Design of Experiments approaches, while expanding knowledge of cell metabolism.

* Promote implementation of media in manufacturing and innovate new approaches to improve and streamline manufacturing operations.

* Collaborate cross-functionally to drive results and meet project timelines.

* Document experimental results in reports and present technical and scientific findings internally and externally.

* Contribute to a safe and compliant laboratory work environment.

Education Minimum Requirement:

* B.S. in Chemical Engineering, Biochemical Engineering, Biomedical Engineering, Biotechnology, Biochemistry, Microbiology, or related biological fields with 3+ years of relevant experience; or Master's degree with some relevant experience.

Required Experience and Skills:

* Experience with cell culture aseptic technique, assays, and general laboratory practices.

* Ability to comprehend and execute experiments independently and to organize, analyze, and communicate experimental datasets.

* Basic knowledge of statistical methods or experience with statistical software like JMP .

* Highly motivated individual who enjoys working in the lab and in a team environment.

Preferred Experience and Skills:

* Strong scientific knowledge and background in cell biology, cell metabolism, or process engineering related to microbial or mammalian cell cultures.

* Demonstrated capabilities in understanding and operating bioanalytical techniques to characterize microbial or cell culture processes

* Demonstrated ability to think critically with excellent problem solving and troubleshooting skills.

* Experience operating bioreactors and/or optimizing media for performance of mammalian cell cultures.

* Basic knowledge of statistical methods (Design of Experiments or multivariate data analysis).

* Demonstrated ability to independently prepare technical documents and scientific presentation to capture the development progress, scientific investigation, and technology development output

We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we follow the science that great medicines can make a significant impact to our world. We believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe.

Who we are

We are known as Merck & Co., Inc., Kenilworth, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world.

What we look for

In a world of rapid innovation, we seek brave Inventors who want to make an Impact in all aspects of our business, enabling breakthroughs that will affect generations to come. We encourage you to bring your disruptive thinking, collaborative spirit and diverse perspective to our organization. Together we will continue Inventing For Life, Impacting Lives while Inspiring Your Career Growth.

Invent. Impact. Inspire.

NOTICE FOR INTERNAL APPLICANTS

In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one anothers thinking and approach problems collectively. We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace.

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.
For more information about personal rights under Equal Employment Opportunity, visit:

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We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one anothers thinking and approach problems collectively. We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace.

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Kenilworth, NJ, USA, also known as Merck Sharp & Dohme Corp., Kenilworth, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:

Regular

Relocation:

Domestic

VISA Sponsorship:

Yes

Travel Requirements:

10%

Flexible Work Arrangements:

Shift:

Valid Driving License:

Hazardous Material(s):

Number of Openings:

1
Requisition ID:R107944