Job Description

About AbbVie
AbbVies mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on peoples lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, womens health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn.

The Principal Scientist I, Drug Designer, will apply modern computational methods in the design of strategic molecules and libraries to advance various drug discovery projects across the oncology portfolio. This individual will actively make a major impact on multi-disciplinary teams. This individual must exemplify strong interpersonal skills, have excellent communication skills and a track record in the application of computational chemistry techniques to impact and advance drug discovery programs. This individual will be responsible for contributing to both lead identification and optimization programs using methods encompassing all computational aspects of drug discovery including structure-based and ligand-based drug design (e.g., docking and scoring, pharmacophore modeling, virtual screening), molecular dynamics and quantum mechanics. In addition to molecular modeling, this individual will work together with other scientists at AbbVie to provide expertise in structural data analysis, cheminformatics, and methods development. General knowledge of drug discovery is expected to include a fundamental understanding of ADME properties and how to address such issues as metabolic stability and Cyp induction, for example.

* Effectively function as a principle investigator, generating original technical ideas and research or development strategies.
* Demonstrate creative 'out of the box' thinking to solve difficult problems and champion new technologies to achieve project goals.
* Independently responsible for project science within his/her area of expertise on one or more project teams.
* Make significant contributions to project team through lab based, or other work environments, activities.
* Generate new scientific proposals and lead those efforts. Anticipate and critically evaluate scientific or regulatory advances or competitive threats and respond with appropriate new strategies.
* Recognized and sought out as an expert in his/her discipline within the company and possibly externally.
* Primary author of publications, presentations, regulatory documents and/or primary inventor of patents.
* Present at leading scientific conferences.
* Mentor/supervise a team of one or more and evaluate the performance of those individuals; is accountable for the effective performance of the team/individuals.

Qualifications
* BS or equivalent education and extensive, typically 14+ years of experience; MS or equivalent education with typically 12+ years of experience; PhD with typically 6+ years of experience in area or scientific area of discipline.
* Demonstrated ability to function as a principle investigator, generating original technical ideas and research or development strategies.
* Demonstrate creative 'out of the box' thinking to solve difficult technical problems and champion new technologies to achieve project goals.
* Recognized and sought out as an expert in his/her discipline within the company and possibly externally.
* Experienced and demonstrated success as primary author of publications, presentations, regulatory documents and/or primary inventor of patents.
* Demonstrated scientific communication and presentation skills by presenting at leading scientific conferences.

Significant Work Activities
N/A
Travel
Yes, 5 % of the Time
Job Type
Experienced
Schedule
Full-time
Job Level Code
M
Equal Employment Opportunity
At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.