Job Description

At Bristol Myers Squibb, we are inspired by a single vision transforming patients lives through science. In oncology, hematology, immunology and cardiovascular disease and one of the most diverse and promising pipelines in the industry each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

Scientist Process Development Analytics

At Bristol Myers Squibb, we are inspired by a single vision transforming patients lives through science. In oncology, hematology, immunology and cardiovascular disease and one of the most diverse and promising pipelines in the industry each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

Job Description:

Global Process Development Analytics team at Bristol Myers Squibb is seeking for a talented scientist. The candidate will get an opportunity to engage in developing cutting-edge analytical technologies at a world-class biologics process analytical development environment.

The responsibilities include,

* Development & Implementation of Process Analytical Technology (PAT) Tools

The role will involve the development, qualification and implementation of vibrational spectroscopy (FT-IR, Raman, and NIR) and multivariate data analysis (MVDA) based PAT capabilities for real time monitoring of bioprocess. The scope of the projects may include establishing Closed-loop process control and the use of advance data interrogation techniques such as machine learning and deep learning as necessary. The candidate will work with cross functional teams within the Biologics Development organization including but not limited to Analytical, Upstream, Downstream, IT and Automation to deliver results.

* Process Analytical Support on Late-Stage Commercial Development Projects

This function is focused on providing analytical testing support to late-stage biologics process development projects. The successful candidate will work closely with process development (Upstream & Downstream) groups to align with their testing needs. Typical analytical testing support includes the execution of SOP-driven methods (HPLC, UPLC, CE-SDS, and iCE...etc.), data analysis, interpretation and reporting of results in timely manner.

Key Responsibilities:

* Work collaboratively with analytical and process stakeholders to establish vibrational spectroscopy and MVDA based PAT capabilities for real time monitoring and control of bioprocess.
* Provide analytical testing support on late-stage biologics process development projects.
* Contribute on data management, visualization and interrogation initiatives.
* Gain internal and external visibility through high quality publications and presentations.

Qualifications:

The successful candidate will have,

* Ph.D. in Chemical Engineering, Analytical Chemistry or relevant discipline with 0-2 years or M.Sc. with 4+ years of relevant experience in Biopharmaceutical or Pharmaceutical industry.
* A strong background in employing MVDA modeling techniques including but not limited to PCA, PLS, SVM, and Cluster analysis of vibrational spectroscopic data (FT-IR, Raman, NIR).
* Expertise of using one or more of the following MVDA software platforms; MATLAB, Unscrambler, SIMCA, Python and/or OPUS.
* Well experienced in using one or more of the following data visualization packages; TIBCO Spotfire, Tableau, and/or CMET.
* A proven track record of accomplishments through scientific publications, presentations and project completion records.
* Knowledge and expertise in using Closed-loop process control, machine learning and deep learning application for bioprocess are highly desirable but not required.
* Knowledge and expertise on HPLC, UPLC, CE-SDS, and iCE are desirable, but not required. Must be willing to learn these techniques based on the business function needs.

The candidate must be,

* A team player with collaborative spirit.
* Able to effectively communicate among stakeholders, collaborators, and peers.
* A quick learner and should be able to drive projects independently.

Job Location: Devens, MA.

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.