Scientist I, Technical Development
Posted on: 18 Jan 2021
Cambridge, MA
Job Description
Job Description
Biogen is seeking a highly motivated scientist to develop and execute cell line engineering strategies to support diverse bioassays that characterize both recombinant protein and gene therapy products in the Analytical Development department.
Responsibilities:
* The individual will work to establish platform cell lines and screening methods to support functional bioassays for various drug products. The candidate will collaborate closely with project scientists on designing and engineering of product-specific cell lines to impact portfolio programs.
* Responsibilities include design and implementation of experiments, data analysis, report writing, and reviewing, delivering technical presentations and mentoring junior scientists. The individual will also be involved in new technology evaluation and implementation.
* The position requires an ability to work independently in a highly interdisciplinary environment, as well as active interaction and collaboration with group members and project team scientists.
Qualifications
* Requires extensive experience with cell line engineering, lentiviral vectors and CRISPR technology.
* Requires proficiency in molecular and cellular techniques, including cell culture, molecular cloning, flow cytometry and fluorescent microscopy.
* Requires experience in assay development and method troubleshooting.
* Requires excellent written and oral communication skills, as well as bioassays in 96-well format.
* Experience with AAV is highly desirable.
Education:
Ph.D. in neuroscience, cellular biology or related field with 0-2 years of post-degree work experience or M.S. with 4-6 years of relevant experience or B.S. with 6-8 years of relevant experience. Industry experience is preferred.
Additional Information
Biogen is seeking a highly motivated scientist to develop and execute cell line engineering strategies to support diverse bioassays that characterize both recombinant protein and gene therapy products in the Analytical Development department.
Biogen
Cambridge, MA
Biogen Inc. discovers, develops, manufactures, and delivers therapies for treating neurological and neurodegenerative diseases worldwide. The company offers TECFIDERA, AVONEX, PLEGRIDY, TYSABRI, and FAMPYRA for the treatment of multiple sclerosis (MS); SPINRAZA for the treatment of spinal muscular atrophy; and FUMADERM for the treatment of plaque psoriasis. It also provides BENEPALI, an etanercept biosimilar referencing ENBREL; FLIXABI, an infliximab biosimilar referencing REMICADE; and IMRALDI, an adalimumab biosimilar referencing HUMIRA. In addition, the company offers RITUXAN for the treatment of non-Hodgkin's lymphoma, chronic lymphocytic leukemia (CLL), rheumatoid arthritis, two forms of ANCA-associated vasculitis, and pemphigus vulgaris; RITUXAN HYCELA for non-Hodgkin's lymphoma and CLL; GAZYVA to treat CLL and follicular lymphoma; and OCREVUS for the treatment of primary progressive MS and relapsing MS, and other anti-CD20 therapies.
Further, it is involved in developing BIIB098, Opicinumab, and BIIB061 for MS and neuroimmunology; Aducanumab, Elenbecestat, BAN2401, BIIB092, BIIB076, and BIIB080 to treat Alzheimer's disease and dementia; BIIB092 and BIIB054 for treating Parkinson's disease and movement disorders; BIIB067, BIIB078, and BIIB110 to treat neuromuscular disorders; BIIB093, TMS-007, and Natalizumab to treat acute neurology; BIIB104 for treating neurocognitive disorders; BIIB074 and BIIB095 for pain; and Dapirolzumab pegol, BG00011, and BIIB059 for treating other diseases, which are under various stages of development.
The company offers products through its sales force and marketing groups. Biogen Inc. has collaboration agreements with Genentech, Inc., Eisai Co., Ltd., Alkermes Pharma Ireland Limited, Bristol-Myers Squibb Company, Acorda Therapeutics, Inc., AbbVie Inc., C4 Therapeutics, University of Pennsylvania, Applied Genetic Technologies Corporation, and others. The company was founded in 1978 and is headquartered in Cambridge, Massachusetts.
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IndustryBiotechnology
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No. of Employees7,800
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Website
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Jobs Posted445
